Join Us

Voyager is looking for exceptional individuals who share our passion for developing life-changing gene therapies for CNS disorders.

Current Openings

Associate Director Clinical Operations ( on-site )

Voyager Therapeutics is seeking an exceptional Associate Director, Clinical Operations, to partner closely with internal/external team members and vendors to ensure all assigned clinical trials are conducted per protocol, in a timely fashion and in a manner compliant with SOPs, ICH/GCP/regulatory guidelines, company goals and established study budgets. This position reports to the Senior Director of Clinical Operations.

Responsibilities:

  • Responsible for clinical operation timelines, and planning activities for each clinical study. Develop and mentor clinical staff and consultants, and secure sufficient resources to support the company’s goals and objectives.
  • Ensure all functions, both internal and external are set up and managed to enable efficient start-up of sites
  • Comprehensive oversight of day-to-day operational aspects of assigned clinical trial(s)
  • Management of Clinical Research Organization (CRO) interactions, including sponsor oversight of relevant functional activities (e.g., study management, monitoring, site management, and project master files).
  • Develop and /or review study related documents ( ie. consent forms, study manuals, study aids, etc. )
  • Identify potential vendors, RFP proposal processes
  • Works with CRO/ vendors to develop and/or revise scope of service agreements, budgets, plans and detailed timelines and ensures that performance expectations are met.
  • Drive consistent monitoring of study progress: ensuring compliance with relevant regulations and guidelines by maintaining regular contact with external vendors, including CRAs as applicable.
  • Complete sponsor’s review of monitoring reports and periodic review of data quality.
  • Identifying potential study issues, and proactively recommending and implementing solutions or corrective actions as needed.
  • Assist with overall study budget development for new studies (e.g. CRO, Investigator fees, pass through fees) and providing information conjunction with the Finance Department
  • Ensure budgets for external services are tracked by clinical operations to provide status regarding contract to budget actual
  • Assist with budget forecasting and accruals as requested
  • Act as primary resource for investigational sites; reviewing investigator contracts and site payments.
  • 15 % travel to CRO/vendors facilities and/or investigative sites to train and assess study team and CRAs.
  • Organizing and managing internal team meetings and other trial-specific meetings.
  • Participate in ongoing development, review and implementation of departmental SOPs and processes.

Qualifications:

  • BS/BA degree in science or similar area.
  • 8-10 years of experience required managing clinical trials for or within the biotech or pharmaceutical industry, including CRO/vendor management, monitoring of budget scope, clinical site monitoring, and knowledge of basic data management/biostatistics processes including Electronic Data Collection (EDC) and Pharmacovigilance
  • Management of Phase I-III clinical trials, including multi-center, and multi-country registration trials

  • The ideal candidate will have a minimum of 5 years managing internal and external contract operations in the biotechnology industry desired.

  • Experience with compliance issues, corrective action procedures and strong understanding of FDA Regulations, GCP and/or SOPs in a clinical operations context

  • Excellent oral and written communications.

  • Strong computer skills including knowledge of Microsoft Excel, Word, Powerpoint and Outlook.
  • Ability to work within established timelines, in a fast paced environment.
  • Excellent organizational and priority management skills.
  • Good interpersonal skills and ability to deal with people at all levels with sensitivity and tact.
  • Prior CNS or gene therapy experience preferred.
  • Travel up to 15% as needed ( Domestic/ Int’l )

Please no agency referrals, calls or unsolicited resumes accepted by Voyager Therapeutics

 
To apply, email careers@voyagertherapeutics.com

Voyager Therapeutics is a clinical-stage gene therapy company developing life-changing treatments for severe diseases of the central nervous system. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector engineering and optimization, manufacturing and dosing and delivery techniques. The company’s pipeline is focused on severe CNS diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Friedreich’s ataxia, Huntington’s disease and spinal muscular atrophy (SMA). Voyager has broad strategic collaborations with Sanofi Genzyme, the specialty care global business unit of Sanofi, and the University of Massachusetts Medical School. Our founders include scientific and clinical leaders in the fields of adeno-associated virus (AAV) gene therapy, expressed RNA interference and neuroscience. Our management team has deep expertise and a track record of building exceptional life science companies.

Senior / Research Associate, Molecular Biology- Vector Engineering

Voyager Therapeutics Vector Engineering Team is seeking a highly motivated Senior Research Associate with molecular and cellular biology techniques to provide  assistance to scientists and work as a part of the vector engineering group.The successful candidate will work largely independently on a daily basis, and yet work closely with the scientist who supervises his/her work.

The individual will be responsible for performing molecular biology and cell biology work, including mammalian cell culture, cell transfection, DNA/RNA extraction from cells and animal tissues, RT-PCR, qPCR, DNA plasmid construction, production and purification. The qualified candidate will also carry out rAAV vector production, purification and quantification etc. In addition, this person will perform Western blot, ELISA assays and SDS-PAGE. This position reports to the Senior Scientist, Vector Engineering.

Requirements

  • B.S in Biology or Biochemistry or MA in Molecular Biology/ Biochemistry
  • 3-5 years  experience virus/protein purification preferred
  • Preferred experience with viral vectors is preferred, but not essential
  • Previous hands-on experience with molecular and cellular techniques is preferred
  • Completing sponsor’s review of monitoring reports and periodic review of data quality
  • Excellent organizational, critical thinking skills, lab notebook practices and attention to detail are essential
  • Excellent communication skills, with the ability to interact with all levels of staff and with external contacts
  • Ability to accurately synthesize data analysis, communicate and present to broader audience
  • Ability to perform multiple tasks with a well-organized manner

Additional Qualifications

  • Prepare the required materials (plasmids, reagents, cells, etc)
  • Document, compile, and analyze experimental data
  • Attends and actively contribute to team meetings, share results, plan projects and experiments
To apply, email careers@voyagertherapeutics.com

Voyager Therapeutics is a clinical-stage gene therapy company developing life-changing treatments for severe diseases of the central nervous system. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector engineering and optimization, manufacturing and dosing and delivery techniques. The company’s pipeline is focused on severe CNS diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Friedreich’s ataxia, Huntington’s disease and spinal muscular atrophy (SMA). Voyager has broad strategic collaborations with Sanofi Genzyme, the specialty care global business unit of Sanofi, and the University of Massachusetts Medical School. Our founders include scientific and clinical leaders in the fields of adeno-associated virus (AAV) gene therapy, expressed RNA interference and neuroscience. Our management team has deep expertise and a track record of building exceptional life science companies.

Research Associate – Neuroscience  ( in -vivo )

Voyager Therapeutics seeks an experienced and highly motivated junior level in vivo research Associate to contribute to its research team at its facility in Cambridge, Massachusetts. This is an ideal position for an individual with excellent in vivo skills in basic rodent procedures and rodent surgery, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. This is a hands-on position for a person committed to helping the group conduct innovative drug discovery research while meeting deadlines and company goals. We are seeking a person who is enthusiastic about biomedical research, is capable of working independently, as well as collaboratively with other scientists and team members. Successful candidates should have extensive prior hands-on expertise with small animal handling and manipulation/restraint to include procedures not limited to in vivo: dosing, measuring, weighing, and surgeries, necropsy, sampling which may include PK/PD and tissue preparation for histology analysis. The candidate should also be able to independently execute experiments and have good communication and interpersonal skills. Prior hands-on experience in qRT-PCR, western, and/or ELISA methods is a plus.

Requirements

  • B.S. in Life Sciences or related
  • 3-5 years In vivo experience in the biotech/pharmaceutical industry is preferred
  • Minimum 3 years of a hand-on laboratory experience with in a range of in vivo techniques including rodent handling, administration of therapeutic agents by various routes (i.e. IV, IP, etc.), observation, transcardial perfusion, blood collection, necropsy and tissue collection and tissues preparation for biochemical assays is required
  • Experience with stereotaxic surgery, and CNS tissue collection is a plus
  • Experience with animal study design, documentation, execution of experiments and data analysis
  • Ability to be highly productive in a fluid and fast-paced work environment
  • The candidate must be team oriented, self-motivated with strong organizational skills

Strongly Preferred

  • Experience on cross-functional therapeutic program team
  • Experience within a start-up or small biotech environment
To apply, email careers@voyagertherapeutics.com

Voyager Therapeutics is a clinical-stage gene therapy company developing life-changing treatments for severe diseases of the central nervous system. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector engineering and optimization, manufacturing and dosing and delivery techniques. The company’s pipeline is focused on severe CNS diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Friedreich’s ataxia, Huntington’s disease and spinal muscular atrophy (SMA). Voyager has broad strategic collaborations with Sanofi Genzyme, the specialty care global business unit of Sanofi, and the University of Massachusetts Medical School. Our founders include scientific and clinical leaders in the fields of adeno-associated virus (AAV) gene therapy, expressed RNA interference and neuroscience. Our management team has deep expertise and a track record of building exceptional life science companies.

Voyager Therapeutics is seeking an exceptional Senior Clinical Trial Manager to partner closely with internal/external team members and vendors to ensure that assigned clinical trials are conducted per protocol, in a timely fashion and in a manner compliant with SOPs, ICH/GCP/regulatory guidelines, company goals and established study budgets. This position reports to the Senior Director of Clinical Operations.

Responsibilities:

  • Ensure all functions, both internal and external are set up and managed to enable efficient start-up of sites
  • Comprehensive oversight of day-to-day operational aspects of assigned clinical trial(s)
  • Management of Clinical Research Organization (CRO) interactions, including sponsor oversight of relevant functional activities (e.g., study management, monitoring, site management, and project master files).
  • Initiate RFP proposal processes
  • Works with CRO/ vendors to develop and/or revise scope of service agreements, budgets, plans and detailed timelines and ensures that performance expectations are met.
  • Drive consistent monitoring of study progress: ensuring compliance with relevant regulations and guidelines by maintaining regular contact with external vendors, including CRAs as applicable.
  • Complete sponsor’s review of monitoring reports and periodic review of data quality.
  • Identifying potential study issues, and proactively recommending and implementing solutions or corrective actions as needed.
  • Assist with overall study budget development for new studies (e.g. CRO, Investigator fees, pass through fees) and providing information conjunction with the Finance Department
  • Act as primary resource for investigational sites; reviewing investigator contracts and site payments.
  • 15 % travel to CRO/vendors facilities and/or investigative sites to train and assess study team and CRAs.

Qualifications:

  • BS/BA degree in science or similar area.
  • 7-10 years of experience required managing clinical trials for or within the biotech or pharmaceutical industry, including CRO/vendor management, clinical site monitoring, and knowledge of basic data management/biostatistics processes including Electronic Data Collection (EDC) and Pharmacovigilance
  • Management of Phase I-III clinical trials, including multi-center, and multi-country registration trials
  • Experience with compliance issues, corrective action procedures and strong understanding of FDA Regulations, GCP and/or SOPs in a clinical operations context
  • Excellent oral and written communications.
  • Strong computer skills including knowledge of Microsoft Excel, Word, Powerpoint and Outlook.
  • Ability to work within established timelines, in a fast paced environment.
  • Excellent organizational and priority management skills. Good interpersonal skills and ability to deal with people at all levels with sensitivity and tact.
  • Prior Biotechnology, CNS or gene therapy experience preferred.
  • Travel up to 15% as needed ( Domestic/ Int’l
  • Voyager Therapeutics is not accepting agency referrals, calls or unsolicited resumes accept
 
To apply, email careers@voyagertherapeutics.com

Voyager Therapeutics is a clinical-stage gene therapy company developing life-changing treatments for severe diseases of the central nervous system. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector engineering and optimization, manufacturing and dosing and delivery techniques. The company’s pipeline is focused on severe CNS diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Friedreich’s ataxia, Huntington’s disease and spinal muscular atrophy (SMA). Voyager has broad strategic collaborations with Sanofi Genzyme, the specialty care global business unit of Sanofi, and the University of Massachusetts Medical School. Our founders include scientific and clinical leaders in the fields of adeno-associated virus (AAV) gene therapy, expressed RNA interference and neuroscience. Our management team has deep expertise and a track record of building exceptional life science companies.

Senior Medical Director, Neurosciences

The Medical Director will lead the formulation of clinical development plans and the planning, execution, analysis and interpretation of all clinical studies to support those plans. The candidate will lead cross-functional teams to generate, deliver, and disseminate high-quality clinical data supporting the overall development strategy for one or more programs.  The initial focus will be on CNS indications currently in the Voyager pipeline.

Responsibilities include, but not limited to;

  • Provide strategic medical leadership that integrates knowledge in gene therapy, basic and clinical neuroscience
  • Formulate clinical development plans (CDP) that integrate scientific rationale, clinical need, clinical measurement approaches, statistical rigor, regulatory and payor requirements, and company strategy
  • Develop and implement high quality clinical studies to support the CDP including biomarker and translational studies, natural history studies, and clinical trials
  • Participate in interpretation of data analyses of clinical trial results and authoring clinical trial reports
  • Provide medical input into regulatory document preparation
  • Direct publication planning, advisory board meetings and training programs
  • Lead clinical study teams
  • Provide medical monitoring, safety assessment and overall oversight for all clinical studies supporting the CDP
  • Establish and operate within appropriate timelines and   budgets for clinical studies
  • Develop and maintain strong relationships with program counterparts in internal functions as well as external collaborative relationships
  • Present at investigator meetings, advisory meetings, regulatory meetings, and represent Voyager at professional meetings
  • Contribute medical leadership and guidance to business development efforts

Essential Requirements:

  • Medical Doctor (M.D.), Doctor of Osteopathy (D.O.), or non-US equivalent of M.D. degree with specialty training in neurology or a neuroscience field
  • Minimum 7 years of clinical trial experience and at least 3 years of pharmaceutical/biotechnology clinical development experience in neuroscience. Pediatric development experience is a plus
  • Extensive knowledge of clinical trial methodology, regulatory and compliance requirements governing clinical trials, and experience in development of clinical strategy and the design of study protocols. Formal training in clinical research methods is a plus
  • Must possess excellent oral and written English communication skills
  • High integrity and proven leadership skills and ability to bring out the best in others on a cross-functional team
  • Ability to prioritize across several complex clinical research studies and programs
  • Demonstrated strategic and critical thinking skills
  • Ability to interact externally and internally to support the scientific and business strategy
  • Ability to exercise judgment and address complex problems and create solutions across multiple projects
To apply, email careers@voyagertherapeutics.com

To apply or learn more about career opportunities at Voyager Therapeutics, please email careers@voyagertherapeutics.com.

Note to Employment Agencies: Please do not forward agency resumes. Voyager Therapeutics is not responsible for any fees related to resumes that are unsolicited and out of executed contracts.

Voyager Therapeutics will only accept job applications from candidates who are properly documented with authorization to work in the United States.

Equal Opportunity Employer M/F/D/V