Science
Revolutionizing delivery
across the blood-brain barrier.
Our Platform: TRACER
Reaching CNS targets once thought unreachable.
Voyager’s TRACER™ (Tropism Redirection of AAV by Cell-type-specific Expression of RNA) capsid discovery platform is a broadly applicable, RNA-based screening platform that enables rapid discovery of AAV capsids with robust penetration of the blood-brain barrier and enhanced central nervous system (CNS) tropism in multiple species, including non-human primates (NHPs).
Non-Viral Approaches
Multiple modalities to treat neurological diseases.
“I love how we all get to collaborate, even though we are on different teams.”
Recent Publications & Presentations
ADPD 2024:
Intravenous administration of BBB-penetrant AAV containing primary artificial microRNA targeting tau reduces tau broadly and robustly in hTau mouse brain
Pharmacokinetics and tolerability of VY-TAU01, an anti-tau antibody for the treatment of Alzheimer’s disease, in P301S mouse and nonhuman primate
In Vivo Gene Therapy and Genome Editing Summit 2023:
Iterative Evolution of Cross-Species BBB-Penetrant Capsids
BioProcessing Summit 2023:
Rapid HEK Platform Scale Up to 200 L Using kLa Modeling
Our Pipeline
Partnerships
Our allies in realizing the potential of neuro-genetic medicines