Voyager Therapeutics plans to develop life-changing gene therapies from discovery, preclinical and clinical development, through to commercialization. We focus on people living with severe neurological diseases that lack safe and effective treatment options, particularly in the areas of Huntington’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS) called SOD1, Friedreich’s ataxia, Alzheimer’s disease, and other tauopathies related to defective or excess aggregation of tau protein in the brain.
Voyager’s mission is to develop and deliver life-changing therapies to people around the world living with severe neurological diseases. This begins with a commitment to discovery, research, development and manufacturing, and extends to our engagement with patients, healthcare providers, caregivers and advocacy organizations.
Voyager innovates and invests in novel adeno-associated virus (AAV) vector engineering and optimization, manufacturing that includes a baculovirus production system for producing AAV vectors at scale in insect-derived cells, and dosing that includes intraparenchymal, intrathecal and intravenous delivery techniques.
Our management team and founders represent some of the most esteemed scientific and clinical leaders in the fields of AAV gene therapy, expressed RNA interference, neuroscience preclinical and clinical development, and manufacturing.
We have broad strategic collaborations with Neurocrine Biosciences and the University of Massachusetts Medical School (UMMS). We have also entered into license and other agreements with UMMS and the University of California San Francisco to access relevant technology and data.
We actively seek collaborators and licensing opportunities to explore certain programs, geographies and technologies.