Scientist I, Neuroscience

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Scientist I, Neuroscience

Voyager Therapeutics is developing life-changing gene therapies for fatal and debilitating diseases of the nervous system. Voyager Therapeutics is developing life-changing gene therapies for fatal and debilitating diseases of the central nervous system. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector engineering and optimization, manufacturing and dosing and delivery techniques. The company’s pipeline is focused on severe CNS diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Huntington’s disease, Friedreich’s ataxia, Alzheimer’s Disease and neuropathic pain.

We are currently seeking an experienced and highly motivated Scientist I who shares our passion for the promise of gene therapy. The successful candidate will work with our multidisciplinary team in Cambridge, Massachusetts. This is an ideal position for an individual with a strong background in neurodegeneration, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.

Responsibilities:

  • The individual will oversee external collaborations with academic labs/CROs
  • S/he will directly work at the bench and be responsible for development and implementation of a variety of assays supporting therapeutic programs and platform discovery research
  • This individual will have extensive prior experience assessing CNS pharmacological readouts including biochemical assay development and implementations (ELISA, LC-MS, RT-qPCR, etc.)

Requirements:

  • A Master’s degree with a minimum of 8 years of experience or a PhD in the field of biology or related discipline is required
  • Extensive experience in all aspects of assay design, development, optimization, validation, and implementation to support gene therapy discovery programs (i.e. RT-qPCR, LC-MS, and ELISA)
  • In vitro skills including general molecular and cellular biology methods, cell-based assays and ex vivo tissue analysis from animal models
  • Current on relevant published literature and developments in the field
  • Proactive, flexible, and able to thrive in a fast-paced team environment
  • Comfortable working on and prioritizing multiple projects
  • Strong verbal and written communication skills and capable of routinely interpreting data and making presentations to diverse groups within Research and Development

 Preferred:

  • Knowledge of assay development in context of preclinical PK-PD evaluation
  • Drug discovery/pharmacology experience with gene therapy and viral vectors
  • Experience with preclinical animal studies including design and execution of test article dosing via various administration routes and sample collection
  • Demonstrated scientific leadership, and strong interpersonal and coaching skills through team roles and mentoring of scientists
  • Work experience within a cross-functional and matrixed organization and/or a highly collaborative research environment

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