Scientist I/Scientist II, Molecular Biology

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Voyager Therapeutics is developing life-changing gene therapies for fatal and debilitating diseases of the nervous system. Voyager Therapeutics is developing life-changing gene therapies for fatal and debilitating diseases of the central nervous system. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector engineering and optimization, manufacturing and dosing and delivery techniques. The company’s pipeline is focused on severe CNS diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Huntington’s disease, Friedreich’s ataxia, Alzheimer’s Disease and neuropathic pain.

Voyager Therapeutics seeks a highly motivated and experienced molecular biologist to contribute to its research team at its facility in Cambridge, Massachusetts. This is an ideal position for an individual with a strong background in early protein drug development (especially AAV gene therapy), who has a can-do attitude and strong work ethic, and thrives in a team-oriented, fast-paced, and cross-disciplinary small biotech environment.

Responsibilities: 

  • Responsible for experimental design, execution, data analysis and reports (both written and verbal) for AAV platform discovery research as well as therapeutic programs
  • Conduct studies in-house and with collaborators and to manage studies conducted at contract research organizations
  • Extensive prior hands-on expertise in molecular and cellular techniques, and significant experience with lead identification/optimization are required

Requirements:

  • Master’s Degree and a minimum of 5 years of work experience OR a Ph.D and a minimum of 0-3 years of work experience in Molecular/Cellular Biology or related 
  • Hands-on experience in drug discovery research, including biologics or gene therapy
  • Extensive hands-on experience with molecular and cellular techniques
  • Proven track record in lead discovery/optimization
  • Significant experience with managing and maintaining collaborations with other laboratories and/or CROs
  • Outstanding problem solving skills
  • Ability to be highly productive in a fluid, fast-paced team environment 

Preferred:

  • Significant experience with early drug development within a small biotech environment
  • Proven track record in antibody/protein engineering, production (small scale) and purification
  • Significant experience with cross-functional therapeutic program teams
  • Working knowledge of RNAi and artificial miRNA construction, optimization and evaluation
  • Experience with writing industry study reports (reports in support of IND a significant plus)
  • Strong publication record in peer-reviewed journals

 

JH