Scientist, Neurobiology (In-Vivo)

Share this job

Scientist, Neurobiology (In-Vivo)

Voyager Therapeutics is developing life-changing gene therapies for fatal and debilitating diseases of the central nervous system. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector engineering and optimization, manufacturing and dosing and delivery techniques. The company’s pipeline is focused on severe CNS diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Huntington’s disease, Friedreich’s ataxia, Alzheimer’s Disease and neuropathic pain.

We are seeking an experienced and highly motivated neurobiologist to contribute to our research team at our facility in Cambridge, Massachusetts. This is an ideal position for an individual with a strong background in in vivo experimental methods and readouts, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. The individual will work in the laboratory and be responsible for experimental execution and data analysis for research studies supporting therapeutic programs and platform discovery research in neurodegenerative disease areas.  The successful candidate will have extensive prior experience in drug discovery in neurodegenerative diseases including hands-on techniques in stereotaxic surgery, in vivo behavioral assays of rodent models, CNS tissue dissection, and tissue analysis (such as RT-qPCR, western blot and ELISA). 

This position is located in Cambridge, MA and reports to a Senior Scientist.

Responsibilities:

  • Drive the planning, design and execution of rodent in vivo experiments
  • Perform rodent in vivo studies including dosing, in-life assessments and tissue analysis (ELISA, western blot, RT-qPCR, immunohistochemistry, etc.)
  • Perform data analyses and deliver data presentations to the research team
  • Ensure maintenance of industry-quality records to provide documentation

Requirements:

  • PhD (1-3 years) or MS (+ 5 years) experience in neuroscience or related discipline
  • Hand-on experience with performing survival surgeries including stereotaxic or direct intraparenchymal injection and rodent behavioral testing to assess motor dysfunction
  • Outstanding problem-solving skills and ability to multi-task
  • Molecular and cell biology experience
  • Excellent communication skills, written and verbal
  • Ability to independently analyze and present data to scientific teams
  • Strong commitment and accountability for completion of projects in accordance with team plans
  • Excellent organizational skills and attention to detail

Strongly Preferred:

  • Experience on cross-functional therapeutic program teams
  • Experience within a start-up or small biotech environment
  • Experience with drug discovery for neurodegenerative diseases, particularly tau-related diseases

2WL