Jim currently serves as chairman of the board of directors of Idera Pharmaceuticals, Orchard Therapeutics, and Pieris Pharmaceuticals, and as a director of Fulcrum Therapeutics. He was previously an entrepreneur-in-residence at Third Rock Ventures, and served earlier as Senior Vice President Strategy and Business Development at Sanofi. He held wide-ranging leadership positions at Genzyme, including Senior Vice President International Development, President of Genzyme Europe, General Manager cardiovascular, and Chairman and CEO of Genzyme Transgenics. Jim started his career at Bain. He has a B.A. from Georgetown, an M.S from the University of Pennsylvania, and a J.D. from Yale.